In pulmonary inflammation caused by viral infection, the loss of RIPK3 reduces the secretion of various inflammatory cytokines and chemokines, especially CXCL10 (also known as interferon-γ-inducible protein 10 [IP-10]) and chemokine ligand 2 (CCL2; monocyte chemoattractant protein 1 [MCP-1]). This evidence concerns the gene CCL2 and inflammation.