Survival analysis of S100 family members in 21 cancer types (Fig. 7A and B) revealed that they served as a favorable prognostic factor in 5 cancer types (CHOL, DLBC, HNSC, OV, and SKCM) (Fig. 7A), while being associated with poor patient survival in 16 cancer types (BLCA, BRCA, GBM, KIRC, KIRP, LAML, LGG, LIHC, LUAD, MESO, PAAD, PCPG, THCA, THYM, UCS, and UVM) (Fig. 7B). Here, S100A1 is linked to cancer.