Ebola virus (EBOV)is an enveloped virus that must fuse with thehost cell membrane in order to release its genome and initiate infection.This process requires the action of the EBOV envelope glycoprotein(GP), encoded by the virus, which resides in the viral envelope andconsists of a receptor binding subunit, GP1, and a membrane fusionsubunit, GP2. The gene discussed is GP2; the disease is infection.