For the risk factors of death from severe COVID-19 infection in patients with AAV, sex, Scr, CRP and COVID-19 vaccination were significant in unadjusted analysis, as patients with severe COVID-19 infection were more likely to be male (OR 11.958 [95% CI 2.661–53.746], P = 0.001) and have higher Scr (OR 2.311 [95% CI 1.313–4.065], P = 0.004) and CRP (OR 1.059 [95% CI 1.014–1.106], P = 0.009) and less likely to have vaccination (OR 4.773 [95% CI 1.063–21.437], P = 0.041). Here, CRP is linked to COVID-19.