The genomic analysis of 110 Indian patients with HNSCC identified 5 additional commonly mutated (10–22% of patients) genes linked to OSCC-GB: USP9X (Ubiquitin-Specific Peptidase 9X), MLL4 (Mixed-lineage leukemia 4), ARID2 (AT- rich interactive domain-containing protein 2), UNC13C (UNC-13 homolog C), and TRPM3 (Transient receptor potential cation channel subfamily M member 3) [110]. The gene discussed is UNC13C; the disease is head and neck squamous cell carcinoma.