PELNVs can apply their innate antitumor capabilities with their significant potential as a drug delivery system since the leukocyte function-associated antigen-1 (LFA-1) and CXC chemokine receptor 2 (CXCR2) found on the plant-derived nano vector surfaces attenuated the inflammation of the tumor target site [100]. This evidence concerns the gene CXCR2 and neoplasm.