Interestingly, compared with biallelic MYO5B deletion or the P660L mutation, this MVID model showed MYO5B(G519R) colocalized with RAB11A in abnormal subapical vesicles in enterocytes, a pattern that was also observed in the patient tissues (Burman et al., 2023). The gene discussed is MYO5B; the disease is microvillus inclusion disease.