Our previous study showed that miR‐429 negatively regulated CRKL expression by binding to CRKL‐3′‐UTR,40, 41 miR‐429 suppressed the migration and invasion of hepatocellular carcinoma (HCC) and clear cell renal cell carcinoma (ccRCC) cells by targeting CRKL via Raf/MEK/ERK pathway41 and SOS1/MEK/ERK/MMP2/MMP9 pathway.40 The gene discussed is SOS1; the disease is hepatocellular carcinoma.