ADCY10 and neoplasm: Residual cells, which survived the anti‐tumor drug treatment and undetectable by standard morphological examination during the remission phase between the cycles of chemotherapy, has attracted attention as one of the crucial factors of tumor drug resistance and tumor recurrence, and thus as a hurdle for anti‐tumor therapy.[45] The fact that living cells with YY2‐induced SAC hyperactivation possessed moderate CIN suggests the possibility that moderate CIN is also involved in drug resistance in residual tumor cells that survived treatment with DNA damage‐inducing agents.