ADCY10 and neoplasm: To identify a novel modulator of the SAC and subsequently tumor cell CIN, we screened genes involved in both “mitotic sister chromatid segregation” and “mitotic spindle assembly checkpoint signaling” from the Gene Ontology (GO) database (QuickGO, http://www.ebi.ac.uk/QuickGO; GO numbers: 0000070 and 0007094; respectively) and obtained 195 genes.