Interestingly, whereas administration of LPS (0.1 μg/kg; Fig. 2A; bar graph shows densitometric analysis) or hypoxia (Fig. 2B; bar graph shows densitometric analysis) did not influence CD163 expression, increase in hepatic oxyhemoglobin (Fig. 2C; bar graph shows densitometric analysis), and iron content (Fig. 2D; bar graph shows densitometric analysis) caused significant enrichment of CD163 in the liver of SCD mice compared to littermate control mice. Here, CD163 is linked to Schnyder corneal dystrophy.