In the study by Raufman et al., ASBT-deficient mice were compared with wild-type mice using azoxymethane (AOM)-induced tumor formation, and an increase in the size and number of colon tumors was observed in SLC10A2-silenced mice compared to the wild type (Raufman et al., 2015). This evidence concerns the gene SLC10A2 and colonic neoplasm.