For example, single-cell chromatin overall omic-scale landscape sequencing (scCOOL-seq) revealed a new set of candidate biomarkers—ZNF667 and ZNF667-AS1, whose expression is associated with better prognosis in patients with pancreatic ductal adenocarcinoma by influencing the proliferation of cancer cells (Fan et al., 2022). The gene discussed is ZNF667; the disease is pancreatic ductal adenocarcinoma.