For example, single-cell chromatin overall omic-scale landscape sequencing (scCOOL-seq) revealed a new set of candidate biomarkers—ZNF667 and ZNF667-AS1, whose expression is associated with better prognosis in patients with pancreatic ductal adenocarcinoma by influencing the proliferation of cancer cells (Fan et al., 2022). This evidence concerns the gene ZNF667 and cancer.