MET and breast carcinoma: The same group also found that α-CBT-diol has the antiproliferative, anti-migratory and anti-invasive effects against multiple breast cancer cell lines which the c-Met overexpressing MDA-MB-231 breast cancer cells are the most sensitive, indicating that α-CBT-diol may be a novel c-Met inhibitors for the c-Met dependent malignancies therapy (Ebrahim et al., 2016).