CD8A and head and neck cancer: Similarly, various radiomic signatures associated with CD8 T cells were identified in a systematic review by Ramlee et al.95 related to various cancers including glioma (high and low-grade), gastrointestinal cancer, head and neck cancer, hepatobiliary cancer, lung cancer, breast cancer, and melanoma and their respective CD8 T-cell-related radiomic signature obtained from imaging modalities such as PET, CT, and MRI.