To further ascertain gal-3’s prognostic relevance in DCM, this study conducted a meta-analysis to evaluate: (1) the predictive value of gal-3 alone for MACEs in DCM patients, and (2) the predictive capability of gal-3 combined with LGE for MACEs, compared to LGE alone. This evidence concerns the gene LGALS3 and familial dilated cardiomyopathy.