Therefore, the study evaluated the expression of gal-3 in LGE(+) and LGE(-) groups, and found that the level of gal-3 in LGE(+) group was higher than that in LGE(-) group, which indicated gal-3 may be related to myocardial fibrosis in DCM patients in LGE(+) group, and indicated that the combination of gal-3 and LGE can significantly enhance the prediction of MACEs. Here, LGALS3 is linked to familial dilated cardiomyopathy.