The keywords used were as follows: chronic kidney disease, mitophagy, renal fibrosis, mitochondria, PINK1, Parkin, FUNDC1, BNIP3/Nix, cardiolipin, obesity-induced CKD, hyperuricemia-induced CKD, diabetes mellitus-induced CKD, UUO, hyperuricemic nephropathy, diabetes-induced CKD, membranous glomerulonephritis-induced CKD, cisplatin-induced CKD. The gene discussed is PRKN; the disease is hyperuricemia.