Of these, ALDOB, WNT11, MSLN, RAC3, and IL1RN have known roles in CRC (54–58), FBLX16 has known roles in other cancers (59, 60), and SLC38A11 and WBSCR27 are relatively uncharacterized (61–63). This evidence concerns the gene METTL27 and colorectal carcinoma.