IGHE and asthma: Diagnostic criteria have been proposed for ABPA, including a history of asthma, specific IgE levels for A. fumigatus higher than 0.35 kUA L−1, total IgE levels greater than 1000 IU/mL, and at least two of the following criteria: temporary or persistent pulmonary infiltrates, peripheral blood eosinophil count exceeding 500 cells/μL, and the presence of serum precipitins or IgG antibodies against A. fumigatus (139).