TXK and tuberculosis: Notably, cg17984638 (TXK) displayed significantly higher methylation, with an average methylation rate of 78.57% ± 8.5% for TB and 68.64% ± 7.38% for HC, while cg23213327 (RSAD2) and cg11554335 (UBE2L6) demonstrated significantly lower methylation, with average rates of 31.45% ± 8.27% and 41.6% ± 9.57% for TB, and 41.25% ± 7.72% and 51.17% ± 6.77% for HC, respectively.