Barros-Viegas A.T., Carmona V., Ferreiro E., Guedes J., Cardoso A.M.,Cunha P., de Almeida L.P., de Oliveira C.R., de Magalhães J.P.,Peça J., Cardoso A.L. miRNA-31 improves cognition and abolishesamyloid-β pathology by targeting APP and BACE1 in an animalmodel of Alzheimer’s disease. The gene discussed is BACE1; the disease is early-onset autosomal dominant Alzheimer disease.