Consistent with the findings in patients with a fresh hip fracture [26] or hematological disorders undergoing 1-year glucocorticoid therapy (> 7.5 mg/day) [15], as well as in mice exposed to endogenous and exogenous glucocorticoids [14], we identified significant positive correlations between circulating sclerostin levels and BMD measurements in postmenopausal females with GIO. The gene discussed is SOST; the disease is hematologic disorder.