The cg15895391 probe, which is hypomethylated in patient 12 (B) and hypermethylated in the other 5p− patients, is located at 5p15.2, has the TRIO gene that has been linked in the literature with intellectual disability and neurobehavioral problems, including autistic traits and attention deficit hyperactivity disorder (ADHD) [13]. This evidence concerns the gene TRIO and Intellectual disability.