In addition, the expression pattern of six Ras GTPase-activating proteins was shown, five Ras GTPase-activating proteins including NF1, RASA1, RASA3, RASA4 and SYNGAP1 exhibited a dysregulated level in READ, while only the results of RASA4 and SYNGAP1 were obvious due to their log2 FC > 2 (Fig. 2B). The gene discussed is SYNGAP1; the disease is reading.