CTHRC1 and cancer: While exposure to WT-BMDM CM alone induced the expression of several myMAF and vMAF genes, the combination of CM from both WT-BMDMs and cancer cells amplified the induction of Cthrc1, Spp1, and Postn, while suppressing several vMAF genes, indicating an induction of a myMAF phenotype (Fig. 4I).