Next, to further demonstrate the regulation of 37LRP by pJNK in osteosarcoma cells, we treated LRP1–SNRNP25-overexpressing osteosarcoma cells with the pJNK inhibitor SP600125 (5, 10, and 15 μM) and treated the control group with the same concentration of DMSO. The gene discussed is LRP1; the disease is osteosarcoma.