To study the differences of overexpressing the transcription factors in either the tumor cells or the stromal components, stable DsRed+ or DsRed+/Snai1+ or DsRed+/Twist1+ MDA-MB-231 cells and NHDFs were generated by transduction with lentiviral particles (Fig. 8g, Supplementary Fig. 10a, b). Here, TWIST1 is linked to neoplasm.