KEGG enrichment analysis provided a more macroscopic perspective, revealing the roles of these genes in key signaling pathways of breast cancer, such as the PPAR signaling pathway, adipocytokine signaling pathway, regulation of adipocyte lipolysis, insulin resistance, type II diabetes, fat digestion and absorption, cAMP signaling pathway, insulin signaling pathway, and AGE-RAGE signaling pathway in diabetes complications. The gene discussed is INS; the disease is diabetes mellitus.