TLR3 and colitis: The additive/synergistic effect of the combination of TLR3, 7, and 9 inhibition on EBV DNA-exacerbated colitis was assessed based on trends in the DAI, macroscopic assessments of the colon, histological damage grading of H&E-stained colon cross sections, and immunofluorescence staining of pro-inflammatory markers in colon cross sections.