We identified important genes DE in both our in vitro and in vivo infection models consistent with previous studies, namely, TLR3, IFIH1 (MDA5), SOCS1, OASL, DDX60, STAT1, MX1, CMPK2, LY96 (MD-2), STAT1, STAT2, TRIM25, IRF7, and IFIT5. The gene discussed is IRF7; the disease is infection.