At the earlier time points post-infection, we did not observe any overlap with down-regulated mRNAs; however, 27 up-regulated mRNAs were common to all early treatment groups, including TLR3, IFIT5, IFIH1 (MDA5), MX1, RSAD2 (viperin), CMPK2, SOCS1, and SCNN1D. The gene discussed is TLR3; the disease is infection.