CD4 and tuberculosis: According to findings from the SAPiT trial, the TB-IRIS incidence increased prominently following a decline in CD4 count, which was 5.6, 12.3 and 23.1 per 100 person years with CD4 counts > 200 cells/μL, between 50 and 200 cells/μL and <50 cells/μL, respectively [90].