CD4 and tuberculosis: Another meta-analysis of eight randomized controlled trials including 4568 participants that evaluated early versus delayed ART initiation (1–4 weeks vs. 8–12 weeks after initiation of tuberculosis treatment) or deferred ART initiation (after the end of tuberculosis treatment) showed that early ART initiation in PLWH with newly diagnosed pulmonary tuberculosis would improve survival only in those with CD4 counts less than 50 cells/μL, while a mortality benefit from early ART was not found among those with CD4 counts more than 50 cells/μL [34].