The IgG antibody titers against the spike protein (BAU/mL) after vaccination were higher in Bororó village (3.945 BAU/mL vs. 3.865 BAU/mL), participants vaccinated against influenza (4.124 BAU/mL vs. 0.270 BAU/mL), non-smokers (2.806 BAU/mL vs. 1.488 BAU/mL), non-alcohol consumers (2.781 BAU/mL vs. 1.078 BAU/mL), female participants (3.578 BAU/mL vs. 1.793 BAU/mL), and the Guarani ethnic group (3.698 BAU/mL vs. 3.361 BAU/mL) (Figure 2). The gene discussed is CHMP5; the disease is influenza.