CLDN1 and atopic eczema: ↓ Atopic dermatitis symptoms (↓ inflammation, skin erythema, edema, dryness, and keratinocyte hyperplasia) and ↓ immunoglobulin E upregulation; ↓ swelling of subiliac lymph nodes and spleen; ↑ skin barrier integrity (↑ claudin-1 expression, cell-to-cell connections, and improved dilaggrin deficiency)