Among the antioxidants used in this study, RSV, CRC and GTE were able to counteract the increases in the MMP-9 and MMP-2 levels with a different inhibitory capacity, whereas OLI, which was the compound with the lowest antioxidant power, was not able to significantly inhibit the levels of MMP-2 and MMP-9 released in THP-1 supernatants. This evidence concerns the gene MMP2 and colorectal carcinoma.