It is well reported that regardless of the increased PSMA expression on malignant PCa cells, severe accumulation and retention of [177Lu]Lu-PSMA-617 and [225Ac]Ac-PSMA-617 can occur in healthy kidneys and SGs despite them having a much lower PSMA expression [18,19,20]. The gene discussed is FOLH1; the disease is posterior cortical atrophy.