This is in line with the findings of Nuzzo et al., who reported an upregulated expression of HCAR2 in biopsies from IBD patients [13], as well as with Wnorowski et al. and Kaddoura et al., who both found HCAR3 to be upregulated in IBD through the use of microarray data [14,15]. This evidence concerns the gene HCAR3 and inflammatory bowel disease.