Finally, for encephalopathies therapy (see Chapter Nerve-Nerve), acting simultaneously in both the periphery and central nervous system, BPC 157 counteracted various encephalopathies and stomach and liver lesions in non-steroidal anti-inflammatory drugs (NSAIDs)-rats [61,105,106,107,108,109] and insulin-rats [62]. The gene discussed is INS; the disease is Encephalopathy.