MiR-15/16 also repressed the expression of ROR1, a receptor for Wnt5a that promotes cell proliferation in leukemia and anoncoembryonic protein expressed in chronic lymphocytic leukemia (CLL) cells, as miR-15/16 expression is inversely related to ROR1 levels [142]. Here, ROR1 is linked to B-cell chronic lymphocytic leukemia.