Returning to benzaldehyde Schiff bases, the designed molecules have been evaluated for their antimicrobial action [15,16,17,18,19] and for their inhibition of biologically relevant enzymes: human carbonic anhydrase (CA) (and its tumor-related isoforms—CA IX, CA XII) [20,21,22], acetylcholinesterase (AChE) [23,24] and urease [25]. Here, ACHE is linked to neoplasm.