TF and acute myeloid leukemia: To target acute myeloid leukemia cells, where the upregulation of both CD117 and transferrin receptors has been documented, Zhu et al. developed a binary drug delivery system comprising nanoparticles loaded with daunorubicin (DN) and adorned with the CD117 aptamer (Apt) and nanoparticles loaded with luteolin (LUT) and decorated with transferrin (Tf).