To explore the antioxidant capacity of [Gd@C82(OH)22]n nanoparticles, Wang et al. evaluated, among others, the activities of the antioxidant enzymes SOD, CAT, GPx, and glutathione S transferase (GST), as well as the levels of GSH, MDA, and protein thiols, from liver tissue samples, from tumor-bearing mice (induced via subcutaneous implantation of murine hepatoma cells, H22), and from normal mice (control group) [56]. This evidence concerns the gene HPGDS and hepatocellular carcinoma.