CD40 and sarcoma: Exopolysaccharides (EPS) from Cordyceps sinensis induces the expression of MHCII, CD40, CD80, and CD86 in DC sarcoma cells, enhances their ability of antigen uptake, and increases the secretion of IL-12 and TNF-α, thus suggesting that EPS have a critical role in initiating anti-tumour immunity and pro-inflammatory immune modulation [48].