Carrot pomace has also been found to increase the expression of co-stimulatory molecules CD40 and CD80, and the fraction of cells CD11c+MHCII+ cells in BMDCs increase pro-inflammatory cytokine production; in cyclophosphamide-immunosuppressed mice administered with influenza vaccine challenge, it significantly enhanced the efficacy of the influenza vaccine [49]. This evidence concerns the gene ITGAX and influenza.