Further analyses of a second sample group of people with MetS (n = 279) and controls (n = 397) revealed significant associations between MetS and polymorphic loci in the CRP (rs2794521), ADCY3 (rs17799872), GHRL (rs696217), CDKAL1 (rs9295474), BDNF (rs11030107), CHRM4 (rs2067482), CHRM1 (rs2067477), HTR3A (rs1062613), and AKT1 (rs3803300) genes (Table 2). This evidence concerns the gene CHRM1 and metabolic syndrome.