Hence, in our mouse model of asthma, major indicators relating to the asthma model (e.g., airway hypersensitivity, total serum IgE, IFN-γ, IL-4, IL-10, IL-13, and inflammatory cell count in BALF) were detected to evaluate the physiological and biochemical changes induced by the antigen (OVA). The gene discussed is IL4; the disease is asthma.