Moreover, the immunofluorescence staining and Western blot results certified that the expression level of the proinflammatory macrophage activation marker F4/80 (Figure 4A), as well as the p-JNK/JNK and p-IκBα/IκBα in the liver of the HF mice, were all substantially reduced by CLA supplementation (Figure 4B, p < 0.05). Here, MAPK8 is linked to hydrops fetalis.