Results from the expression of genes related to lipid metabolism further demonstrated that the HF+CLA mice had significantly reduced expression levels of genes related to lipogenesis, including CD36, FABP1, SLC27A1, SREBP1 and ACC, and a significantly increased expression of genes involved in fatty acid oxidation, including PPARα, CPT1 and PGC1α, compared with HF mice (Figure 2C,D, p < 0.05). Here, SREBF1 is linked to hydrops fetalis.