MAPK8 and hydrops fetalis: Correspondingly, the gene expressions of proinflammatory cytokine TNF-α, IL-6 and IL-1β and the protein expressions of phosphorylated (p)-JNK/JNK and p-IκBα/IκBα in adipose tissue, which are key inflammatory signaling regulators, were also significantly reduced in HF mice with the supplementation of CLA (Figure 2F,G, p < 0.05).