The gene expression results associated with the WNT/β-catenin signaling pathway, which is implicated in CRC tumorigenesis, showed a significant effect of both OBG and rat health status on the modulation of Wnt1 expression (ANOVA, p < 0.01 and p < 0.05, respectively, Figure 5A). The gene discussed is WNT1; the disease is colorectal carcinoma.