ABCB4 and Hepatic fibrosis: The relationship between Lachnospiraceae and the immune system has previously been described, showing that colonization with Lachnospiraceae in mdr2 −/− mice pre-treated with antibiotics caused a reduction in liver fibrosis, inflammation, and pathobiont translocation, which could be mediated by Lachnospiraceae metabolites, such as SCFA [72].