The infection of these pathogens triggers the rapid accumulation of JA and jasmonoyl-L-isoleucine (JA-Ile), the major bioactive derivative of JA, which activate the downstream signaling to upregulate the production of the defense-related secondary metabolites and proteins in plants, such as alkaloids, phenylpropanoids, terpenoids, and several types of PR proteins [96,97]. Here, TMEM37 is linked to infection.