In a clinical study, PTSD patients exhibited downregulation of certain genes related to the oxidative phosphorylation pathway in the dorsolateral prefrontal cortex, including Atp5e, Cox8a, NADH: ubiquinone oxidoreductase subunit B5 (Ndufb5), and NADH: ubiquinone oxidoreductase core subunit S2 (Ndufs2) [61]. The gene discussed is NDUFS2; the disease is post-traumatic stress disorder.