INS and obesity due to melanocortin 4 receptor deficiency: In DisGeNET from the Enrichr analysis (Figure 4D), the hub gene-related diseases were shown to be insulin resistance, infection, obesity, insulin sensitivity, and tumor initiation, and the potential drugs from the Proteomics Drug Atlas were listed, such as SCH 530348, PHA 767491, AZD8055, 7,8-dihydroxyflavone, and zotarolimus (Figure 4E).