The deep-learning based model was also applied by the group Klein et al. to evaluate different markers of M2 macrophages (CD163 and CD204) together with global immunologic markers (CD4, CD8, CD68, CD38, FOXP3 and CD20) and characterized their intratumoral density in 45 SCLC tumors [69]. This evidence concerns the gene CD163 and small cell lung carcinoma.